HIV/AIDS is a serious health threat for prison populations in many countries, people in prisons still face barriers to accessing evidence-based HIV prevention, testing, treatment and care. Human Dignity Tanzania is aiming at providing prisoners with prevention, care, treatment, and support for HIV/AIDS that is equivalent to that available to people in the community outside of prison. There is much that can be done to reduce the alarming spread of HIV in prisons, as several types of intervention around the world in the past decade have shown. As in other areas of society where the spread of HIV is concerned, it is important, first of all to end denial about what is going on in the prison. Prisoners should be given the necessary information, education and resources to avoid infection. The fact that prisoners are a captive community creates an unusual opportunity for easy access to them, for the purposes of providing them with education and the necessary materials for HIV prevention. All possible steps should be taken to prevent HIV transmission in prison for the sake not only of staff and prisoners, but of society in general. This is due to the fact that what happens at correctional centres directly affects our communities when these citizens come back and are integrated into our society.